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Volume 56(12);  2012 Dec

Editorial

Acknowledgment of Ad Hoc Reviewers
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6075–6079. doi: 10.1128/AAC.02041-12
PMCID:
PMC3497177
Article PDF–81K

Minireview

Importance of the Genetic Diversity within the Mycobacterium tuberculosis Complex for the Development of Novel Antibiotics and Diagnostic Tests of Drug Resistance
Claudio U. Köser, Silke Feuerriegel, David K. Summers, John A. C. Archer, Stefan Niemann
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6080–6087. doi: 10.1128/AAC.01641-12
PMCID:
PMC3497208
Article PDF–215K

Chemistry; Biosynthesis

Structure-Activity Relationships among the Kanamycin Aminoglycosides: Role of Ring I Hydroxyl and Amino Groups
Sumantha Salian, Tanja Matt, Rashid Akbergenov, Shinde Harish, Martin Meyer, Stefan Duscha, Dmitri Shcherbakov, Bruno B. Bernet, Andrea Vasella, Eric Westhof, Erik C. Böttger
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6104–6108. doi: 10.1128/AAC.01326-12
PMCID:
PMC3497201
Article PDF–940K

Mechanisms of Action: Physiological Effects

Effects of 14-Alpha-Lipoyl Andrographolide on Quorum Sensing in Pseudomonas aeruginosa
Li Ma, Xiangyang Liu, Haihua Liang, Yizhou Che, Caixia Chen, Huanqin Dai, Ke Yu, Mei Liu, Luyan Ma, Ching-Hong Yang, Fuhang Song, Yuqiang Wang, Lixin Zhang
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6088–6094. doi: 10.1128/AAC.01119-12
PMCID:
PMC3497202
Article PDF–638K

Mechanisms of Resistance

Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins
Cristina Jiménez-Ortigosa, Vishukumar Aimanianda, Laetitia Muszkieta, Isabelle Mouyna, David Alsteens, Stéphane Pire, Remi Beau, Sven Krappmann, Anne Beauvais, Yves F. Dufrêne, César Roncero, Jean-Paul Latgé
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6121–6131. doi: 10.1128/AAC.00752-12
PMCID:
PMC3497188
Article PDF–1.4M
Genetic and Biochemical Characterization of an Acquired Subgroup B3 Metallo-β-Lactamase Gene, blaAIM-1, and Its Unique Genetic Context in Pseudomonas aeruginosa from Australia
Dongeun Yong, Mark A. Toleman, Jan Bell, Brett Ritchie, Rachael Pratt, Henry Ryley, Timothy R. Walsh
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6154–6159. doi: 10.1128/AAC.05654-11
PMCID:
PMC3497169
Article PDF–668K
β-Lactams Increase the Antibacterial Activity of Daptomycin against Clinical Methicillin-Resistant Staphylococcus aureus Strains and Prevent Selection of Daptomycin-Resistant Derivatives
Shrenik Mehta, Christopher Singh, Konrad B. Plata, Palas K. Chanda, Arundhati Paul, Sarah Riosa, Roberto R. Rosato, Adriana E. Rosato
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6192–6200. doi: 10.1128/AAC.01525-12
PMCID:
PMC3497165
Article PDF–1.4M
The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS
Lucía Fernández, Håvard Jenssen, Manjeet Bains, Irith Wiegand, W. James Gooderham, Robert E. W. Hancock
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6212–6222. doi: 10.1128/AAC.01530-12
PMCID:
PMC3497197
Article PDF–1.1M
Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus
Aashish Srivastava, David Degen, Yon W. Ebright, Richard H. Ebright
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6250–6255. doi: 10.1128/AAC.01060-12
PMCID:
PMC3497154
Article PDF–820K
Effect of Transcriptional Activators SoxS, RobA, and RamA on Expression of Multidrug Efflux Pump AcrAB-TolC in Enterobacter cloacae
Astrid Pérez, Margarita Poza, Jesús Aranda, Cristina Latasa, Francisco Javier Medrano, María Tomás, Antonio Romero, Iñigo Lasa, Germán Bou
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6256–6266. doi: 10.1128/AAC.01085-12
PMCID:
PMC3497196
Article PDF–676K
Fks1 and Fks2 Are Functionally Redundant but Differentially Regulated in Candida glabrata: Implications for Echinocandin Resistance
Santosh K. Katiyar, Ana Alastruey-Izquierdo, Kelley R. Healey, Michael E. Johnson, David S. Perlin, Thomas D. Edlind
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6304–6309. doi: 10.1128/AAC.00813-12
PMCID:
PMC3497156
Article PDF–328K
Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam
Craig J. McPherson, Lisa M. Aschenbrenner, Brian M. Lacey, Kelly C. Fahnoe, Margaret M. Lemmon, Steven M. Finegan, Baswanth Tadakamalla, John P. O'Donnell, John P. Mueller, Andrew P. Tomaras
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6334–6342. doi: 10.1128/AAC.01345-12
PMCID:
PMC3497185
Article PDF–211K
The Inactivation of Intrinsic Antibiotic Resistance Determinants Widens the Mutant Selection Window for Quinolones in Stenotrophomonas maltophilia
Guillermo García-León, María B. Sánchez, José L. Martínez
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6397–6399. doi: 10.1128/AAC.01558-12
PMCID:
PMC3497180
Article PDF–209K
The Sequence-Activity Relationship between Metallo-β-Lactamases IMP-1, IMP-6, and IMP-25 Suggests an Evolutionary Adaptation to Meropenem Exposure
Eleanor M. Liu, Kevin M. Pegg, Peter Oelschlaeger
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6403–6406. doi: 10.1128/AAC.01440-12
PMCID:
PMC3497198
Article PDF–356K
Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2
Claire M. Hull, Oliver Bader, Josie E. Parker, Michael Weig, Uwe Gross, Andrew G. S. Warrilow, Diane E. Kelly, Steven L. Kelly
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6417–6421. doi: 10.1128/AAC.01145-12
PMCID:
PMC3497184
Article PDF–932K
ICESp1116, the Genetic Element Responsible for erm(B)-Mediated, Inducible Resistance to Erythromycin in Streptococcus pyogenes
Andrea Brenciani, Erika Tiberi, Eleonora Morici, Erman Oryaşın, Eleonora Giovanetti, Pietro E. Varaldo
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6425–6429. doi: 10.1128/AAC.01494-12
PMCID:
PMC3497170
Article PDF–760K

Susceptibility

Ceftaroline versus Isolates from Animal Bite Wounds: Comparative In Vitro Activities against 243 Isolates, Including 156 Pasteurella Species Isolates
Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Kerin L. Tyrrell
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6319–6323. doi: 10.1128/AAC.01794-12
PMCID:
PMC3497206
Article PDF–130K
In Vitro Synergy between Clofazimine and Amikacin in Treatment of Nontuberculous Mycobacterial Disease
Jakko van Ingen, Sarah E. Totten, Niels K. Helstrom, Leonid B. Heifets, Martin J. Boeree, Charles L. Daley
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6324–6327. doi: 10.1128/AAC.01505-12
PMCID:
PMC3497179
Article PDF–128K
In Vitro Activities of Antibiotics and Antimicrobial Cationic Peptides Alone and in Combination against Methicillin-Resistant Staphylococcus aureus Biofilms
Emel Mataraci, Sibel Dosler
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6366–6371. doi: 10.1128/AAC.01180-12
PMCID:
PMC3497160
Article PDF–750K
Differences in the Frequency of 23S rRNA Gene Mutations in Mycoplasma pneumoniae between Children and Adults with Community-Acquired Pneumonia: Clinical Impact of Mutations Conferring Macrolide Resistance
Soo Jin Yoo, Hyo-Bin Kim, Sang-Ho Choi, Sang-Oh Lee, Sung-Han Kim, Sang-Bum Hong, Heungsup Sung, Mi-Na Kim
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6393–6396. doi: 10.1128/AAC.01421-12
PMCID:
PMC3497172
Article PDF–127K
Screening of Antifungal Azole Drugs and Agrochemicals with an Adapted alamarBlue-Based Assay Demonstrates Antibacterial Activity of Croconazole against Mycobacterium ulcerans
Nicole Scherr, Katharina Röltgen, Matthias Witschel, Gerd Pluschke
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6410–6413. doi: 10.1128/AAC.01383-12
PMCID:
PMC3497166
Article PDF–447K
Interaction of the Echinocandin Caspofungin with Amphotericin B or Voriconazole against Aspergillus Biofilms In Vitro
Weixia Liu, Lijuan Li, Yi Sun, Wei Chen, Zhe Wan, Ruoyu Li, Wei Liu
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6414–6416. doi: 10.1128/AAC.00687-12
PMCID:
PMC3497162
Article PDF–167K

Antiviral Agents

Identification of Hepatitis C Virus Inhibitors Targeting Different Aspects of Infection Using a Cell-Based Assay
Xuemei Yu, Bruno Sainz, Jr., Pavel A. Petukhov, Susan L. Uprichard
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6109–6120. doi: 10.1128/AAC.01413-12
PMCID:
PMC3497158
Article PDF–2.5M
Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication
Raymond F. Schinazi, Leda Bassit, Marcia M. Clayton, Bill Sun, James J. Kohler, Aleksandr Obikhod, Alla Arzumanyan, Mark A. Feitelson
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6186–6191. doi: 10.1128/AAC.01483-12
PMCID:
PMC3497168
Article PDF–620K
A 90-Day Tenofovir Reservoir Intravaginal Ring for Mucosal HIV Prophylaxis
Todd J. Johnson, Meredith R. Clark, Theodore H. Albright, Joel S. Nebeker, Anthony L. Tuitupou, Justin T. Clark, Judit Fabian, R. Tyler McCabe, Neelima Chandra, Gustavo F. Doncel, David R. Friend, Patrick F. Kiser
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6272–6283. doi: 10.1128/AAC.01431-12
PMCID:
PMC3497207
Article PDF–1.9M
Exacerbation of Influenza Virus Infections in Mice by Intranasal Treatments and Implications for Evaluation of Antiviral Drugs
Donald F. Smee, Mark von Itzstein, Beenu Bhatt, E. Bart Tarbet
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6328–6333. doi: 10.1128/AAC.01664-12
PMCID:
PMC3497157
Article PDF–740K
Short-Term Monotherapy with IDX184, a Liver-Targeted Nucleotide Polymerase Inhibitor, in Patients with Chronic Hepatitis C Virus Infection
Jacob Lalezari, David Asmuth, Arnaldo Casiró, Hugo Vargas, Shannon Lawrence, Gloria Dubuc-Patrick, Jie Chen, Joseph McCarville, Keith Pietropaolo, Xiao-Jian Zhou, John Sullivan-Bólyai, Douglas Mayers
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6372–6378. doi: 10.1128/AAC.01521-12
PMCID:
PMC3497200
Article PDF–345K
Liposome-Mediated Delivery of Iminosugars Enhances Efficacy against Dengue Virus In Vivo
Joanna L. Miller, Ruben Lachica, Andrew C. Sayce, James P. Williams, Manisha Bapat, Raymond Dwek, P. Robert Beatty, Eva Harris, Nicole Zitzmann
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6379–6386. doi: 10.1128/AAC.01554-12
PMCID:
PMC3497178
Article PDF–1.0M

Epidemiology and Surveillance

Rapid Identification of International Multidrug-Resistant Pseudomonas aeruginosa Clones by Multiple-Locus Variable Number of Tandem Repeats Analysis and Investigation of Their Susceptibility to Lytic Bacteriophages
Jérôme Larché, Flavie Pouillot, Christiane Essoh, Balázs Libisch, Monica Straut, Je Chul Lee, Charles Soler, Richard Lamarca, Elodie Gleize, Jérôme Gabard, Gilles Vergnaud, Christine Pourcel
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6175–6180. doi: 10.1128/AAC.01233-12
PMCID:
PMC3497159
Article PDF–748K
Comparison of Genospecies and Antimicrobial Resistance Profiles of Isolates in the Acinetobacter calcoaceticus-Acinetobacter baumannii Complex from Various Clinical Specimens
Ni Tien, Bang-Jau You, Hui-Lan Chang, Hsiu-Shen Lin, Chin-Yi Lee, Tung-Ching Chung, Jang-Jih Lu, Chao-Chin Chang
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6267–6271. doi: 10.1128/AAC.01304-12
PMCID:
PMC3497195
Article PDF–144K
Genetic Markers of Widespread Extensively Drug-Resistant Pseudomonas aeruginosa High-Risk Clones
Gabriel Cabot, Alain A. Ocampo-Sosa, M. Angeles Domínguez, Juan F. Gago, Carlos Juan, Fe Tubau, Cristina Rodríguez, Bartolomé Moyà, Carmen Peña, Luis Martínez-Martínez, Antonio Oliver
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6349–6357. doi: 10.1128/AAC.01388-12
PMCID:
PMC3497190
Article PDF–649K
Multiresistant Uropathogenic Escherichia coli from a Region in India Where Urinary Tract Infections Are Endemic: Genotypic and Phenotypic Characteristics of Sequence Type 131 Isolates of the CTX-M-15 Extended-Spectrum-β-Lactamase-Producing Lineage
Arif Hussain, Christa Ewers, Nishant Nandanwar, Sebastian Guenther, Savita Jadhav, Lothar H. Wieler, Niyaz Ahmed
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6358–6365. doi: 10.1128/AAC.01099-12
PMCID:
PMC3497203
Article PDF–934K
Identification of VanN-Type Vancomycin Resistance in an Enterococcus faecium Isolate from Chicken Meat in Japan
Takahiro Nomura, Koichi Tanimoto, Keigo Shibayama, Yoshichika Arakawa, Shuhei Fujimoto, Yasuyoshi Ike, Haruyoshi Tomita
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6389–6392. doi: 10.1128/AAC.00747-12
PMCID:
PMC3497174
Article PDF–581K
Rapid Identification of Carbapenemase Types in Enterobacteriaceae and Pseudomonas spp. by Using a Biochemical Test
Laurent Dortet, Laurent Poirel, Patrice Nordmann
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6437–6440. doi: 10.1128/AAC.01395-12
PMCID:
PMC3497194
Article PDF–424K

Experimental Therapeutics

Bacterial Resistance to Antisense Peptide Phosphorodiamidate Morpholino Oligomers
Susan E. Puckett, Kaleb A. Reese, Georgi M. Mitev, Valerie Mullen, Rudd C. Johnson, Kyle R. Pomraning, Brett L. Mellbye, Lucas D. Tilley, Patrick L. Iversen, Michael Freitag, Bruce L. Geller
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6147–6153. doi: 10.1128/AAC.00850-12
PMCID:
PMC3497173
Article PDF–202K
Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence Expression In Vivo
Megan L. Falsetta, Marlise I. Klein, José A. Lemos, Bruno B. Silva, Senyo Agidi, Kathy K. Scott-Anne, Hyun Koo
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6201–6211. doi: 10.1128/AAC.01381-12
PMCID:
PMC3497192
Article PDF–1.3M
Identification and Evaluation of Twin-Arginine Translocase Inhibitors
Michael L. Vasil, Andrew P. Tomaras, Arthur E. Pritchard
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6223–6234. doi: 10.1128/AAC.01575-12
PMCID:
PMC3497164
Article PDF–2.5M
Virulent Bacteriophages Can Target O104:H4 Enteroaggregative Escherichia coli in the Mouse Intestine
Damien Maura, Matthieu Galtier, Chantal Le Bouguénec, Laurent Debarbieux
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6235–6242. doi: 10.1128/AAC.00602-12
PMCID:
PMC3497199
Article PDF–2.9M
Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice
E. A. Weinstein, L. Liu, A. A. Ordonez, H. Wang, J. M. Hooker, P. J. Tonge, S. K. Jain
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6284–6290. doi: 10.1128/AAC.01644-12
Correction in:
Antimicrob Agents Chemother. 2013 Jan; 57(1): 678.
PMCID:
PMC3497161
Article PDF–1.7M
Ceftobiprole Efficacy In Vitro against Panton-Valentine Leukocidin Production and In Vivo against Community-Associated Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rabbits
Azzam Saleh-Mghir, Oana Dumitrescu, Aurélien Dinh, Yassine Boutrad, Laurent Massias, Émilie Martin, François Vandenesch, Jérôme Etienne, Gérard Lina, Anne Claude Crémieux
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6291–6297. doi: 10.1128/AAC.00926-12
PMCID:
PMC3497175
Article PDF–335K
Full and Broad-Spectrum In Vivo Eradication of Catheter-Associated Biofilms Using Gentamicin-EDTA Antibiotic Lock Therapy
Ashwini Chauhan, David Lebeaux, Jean-Marc Ghigo, Christophe Beloin
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6310–6318. doi: 10.1128/AAC.01606-12
PMCID:
PMC3497211
Article PDF–4.2M
Targeting Essential Genes in Salmonella enterica Serovar Typhimurium with Antisense Peptide Nucleic Acid
Muhammad A. Soofi, Mohamed N. Seleem
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6407–6409. doi: 10.1128/AAC.01437-12
PMCID:
PMC3497187
Article PDF–115K
Activity of Moxifloxacin, Imipenem, and Ertapenem against Escherichia coli, Enterobacter cloacae, Enterococcus faecalis, and Bacteroides fragilis in Monocultures and Mixed Cultures in an In Vitro Pharmacokinetic/Pharmacodynamic Model Simulating Concentrations in the Human Pancreas
Sabine Schubert, Axel Dalhoff
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6434–6436. doi: 10.1128/AAC.00872-12
PMCID:
PMC3497186
Article PDF–113K

Clinical Therapeutics

Prevention and Treatment of Virulent Bacterial Biofilms with an Enzymatic Nitric Oxide-Releasing Dressing
Imran Sulemankhil, Jorge Gabriel Ganopolsky, Christopher Anthony Dieni, Andrei Florin Dan, Mitchell Lawrence Jones, Satya Prakash
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6095–6103. doi: 10.1128/AAC.01173-12
PMCID:
PMC3497171
Article PDF–1009K
Efficacy of Ceftaroline Fosamil in a Staphylococcal Murine Pneumonia Model
Amira A. Bhalodi, Jared L. Crandon, Donald Biek, David P. Nicolau
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6160–6165. doi: 10.1128/AAC.01078-12
PMCID:
PMC3497181
Article PDF–731K
Effect of Continuous Venovenous Hemofiltration Dose on Achievement of Adequate Vancomycin Trough Concentrations
Erin N. Frazee, Philip J. Kuper, Garrett E. Schramm, Scott L. Larson, Kianoush B. Kashani, Douglas R. Osmon, Nelson Leung
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6181–6185. doi: 10.1128/AAC.00459-12
PMCID:
PMC3497205
Article PDF–350K
Population-Based Study of the Increased Incidence of Skin and Soft Tissue Infections and Associated Antimicrobial Use
Fawziah Marra, David M. Patrick, Mei Chong, Rachel McKay, Linda Hoang, William R. Bowie
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6243–6249. doi: 10.1128/AAC.00649-12
PMCID:
PMC3497163
Article PDF–895K
Dosing Nomograms for Attaining Optimum Concentrations of Meropenem by Continuous Infusion in Critically Ill Patients with Severe Gram-Negative Infections: a Pharmacokinetics/Pharmacodynamics-Based Approach
Federico Pea, Pierluigi Viale, Piergiorgio Cojutti, Mario Furlanut
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6343–6348. doi: 10.1128/AAC.01291-12
PMCID:
PMC3497191
Article PDF–765K
Red Man Syndrome Adverse Reaction following Intravenous Infusion of Cefepime
George Panos, Dionysios C. Watson, Maria Sargianou, Dionysios Kampiotis, Paraskevi Chra
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6387–6388. doi: 10.1128/AAC.01274-12
PMCID:
PMC3497189
Article PDF–1.0M
Effect of Posaconazole on Cyclosporine Blood Levels and Dose Adjustment in Allogeneic Blood and Marrow Transplant Recipients
Isabel Sánchez-Ortega, Lourdes Vázquez, Carmen Montes, Beatriz Patiño, Montserrat Arnan, Arancha Bermúdez, Lucrecia Yáñez, Teresa Caballero, Rafael F. Duarte
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6422–6424. doi: 10.1128/AAC.01489-12
PMCID:
PMC3497182
Article PDF–105K
A Case of Daptomycin-Induced Immune Thrombocytopenia
Charles Grégoire, Caren Brumpt, Delphine Loirat, Nicolas Lau, Cedric Bruel, Francois Philippart, Carine Couzigou, Maité Garrouste-Orgeas, Benoit Misset
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6430–6431. doi: 10.1128/AAC.01787-12
PMCID:
PMC3497155
Article PDF–230K
Stability of Colistimethate Sodium in Aqueous Solution
A. M. Healan, W. Gray, E. J. Fuchs, J. M. Griffiss, R. A. Salata, J. Blumer
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6432–6433. doi: 10.1128/AAC.01079-12
PMCID:
PMC3497204
Article PDF–93K

Pharmacology

Comparison of the In Vivo Pharmacokinetics and In Vitro Dissolution of Raltegravir in HIV Patients Receiving the Drug by Swallowing or by Chewing
Dario Cattaneo, Sara Baldelli, Matteo Cerea, Simona Landonio, Paola Meraviglia, Emanuela Simioni, Valeria Cozzi, Serena Fucile, Andrea Gazzaniga, Emilio Clementi, Massimo Galli, Giuliano Rizzardini, Cristina Gervasoni
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6132–6136. doi: 10.1128/AAC.00942-12
PMCID:
PMC3497176
Article PDF–168K
Comparative In Vitro and In Vivo Efficacies of Human Simulated Doses of Ceftazidime and Ceftazidime-Avibactam against Pseudomonas aeruginosa
Jared L. Crandon, Virna J. Schuck, Mary Anne Banevicius, Marie-Eve Beaudoin, Wright W. Nichols, M. Angela Tanudra, David P. Nicolau
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6137–6146. doi: 10.1128/AAC.00851-12
PMCID:
PMC3497209
Article PDF–1.1M
Influence of the Protein Kinase C Activator Phorbol Myristate Acetate on the Intracellular Activity of Antibiotics against Hemin- and Menadione-Auxotrophic Small-Colony Variant Mutants of Staphylococcus aureus and Their Wild-Type Parental Strain in Human THP-1 Cells
Laetitia G. Garcia, Sandrine Lemaire, Barbara C. Kahl, Karsten Becker, Richard A. Proctor, Paul M. Tulkens, Françoise Van Bambeke
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6166–6174. doi: 10.1128/AAC.01031-12
PMCID:
PMC3497167
Article PDF–1.3M
Therapeutic Drug Monitoring of Posaconazole in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
M. Vaes, M. Hites, F. Cotton, A. M. Bourguignon, M. Csergö, C. Rasson, L. Ameye, D. Bron, F. Jacobs, M. Aoun
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6298–6303. doi: 10.1128/AAC.01177-12
PMCID:
PMC3497193
Article PDF–457K
Effect of PTX3 and Voriconazole Combination in a Rat Model of Invasive Pulmonary Aspergillosis
Pietro Lo Giudice, Silvia Campo, Rita De Santis, Giovanni Salvatori
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6400–6402. doi: 10.1128/AAC.01000-12
PMCID:
PMC3497210
Article PDF–205K

Publisher's Correction

Novel Characteristics of Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains Belonging to Multilocus Sequence Type 59 in Taiwan
Tomomi Takano, Wataru Higuchi, Hassan Zaraket, Taketo Otsuka, Tatiana Baranovich, Shymaa Enany, Kohei Saito, Hirokazu Isobe, Soshi Dohmae, Kyoko Ozaki, Misao Takano, Yasuhisa Iwao, Michiko Shibuya, Takeshi Okubo, Shizuka Yabe, Da Shi, Ivan Reva, Lee-Jene Teng, Tatsuo Yamamoto
Antimicrob Agents Chemother. 2012 Dec; 56(12): 6441. doi: 10.1128/AAC.02059-12
Corrects:
Antimicrob Agents Chemother. 2008 Mar; 52(3): 837–845.
PMCID:
PMC3497183
Correction PDF–63K
Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)