Highlights

Latest research

    1. Neuroscience

    The NeuroML ecosystem for standardized multi-scale modeling in neuroscience

    Ankur Sinha, Padraig Gleeson ... R. Angus Silver
    1. Ecology

    Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing

    Hao Wang, Kai He ... Chaolun Li
    1. Cell Biology

    PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis

    Gang Liu, Yunxuan Hou ... Xiumei Jiang
    1. Evolutionary Biology

    CLOCK evolved in cnidaria to synchronize internal rhythms with diel environmental cues

    Raphael Aguillon, Mieka Rinsky ... Oren Levy
    1. Neuroscience

    Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

    Hao Li, Jingyu Feng ... Jufang He
    CCK released from the neural projections from the rhinal cortex to the motor cortex modulates neural plasticity and facilitates motor skill learning.
    1. Computational and Systems Biology
    2. Developmental Biology

    The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

    Arya Y Nakhe, Prasanna K Dadi ... David A Jacobson
    A mouse model of maturity-onset diabetes of the young illuminates that overactive TALK-1 channels limit β-cell calcium influx through membrane potential hyperpolarization, which blunts insulin secretion and causes glucose intolerance.
    1. Neuroscience

    A dynamic neural resource model bridges sensory and working memory

    Ivan Tomić, Paul M Bays
    Psychophysical measurement and computational modeling show that sensory information cannot contribute directly to a cognitive judgment, but must first be integrated into resource-limited working memory.